Shannen Doherty – 50
She grew to prominence by playing Prue in the Charmed series of the ‘90s and early ‘00s. Since then, Shannen Doherty has kept a balanced and successful career in acting. She has been struggling with her health, however, in the past years. She was diagnosed with cancer in 2016, and a year later she announced that it was on remission. However, in 2020 her cancer apparently came back. The last project in which she acted was the BH90210 series in 2019, and in 2020 she was a guest on the Good Morning America show.